Principle of the Gel System The Matrix Gel system offers a beneficial platform of enhanced sensitivity, specificity and simplicity to the immuno-haematologists and Laboratarians for blood grouping, typing, antibody screening and identification.
Tulip has used its vast experience and resources to develop the Matrix Gel System based on the Gel
column agglutination technology indigenously.
Principle of the Gel System In the gel system, unlike in the tube test the agglutination does not take place in an aqueous phase instead it takes place in specially devised micro tubes, preformed in a plastic card known as the gel card.
The gel column agglutination method is used to detect red cell antigen and antibody reactions in the microtubes which may be neutral or may contain appropriate reagents depending on the application; such as Anti-A, Anti-B, Anti-D, Anti Human Globulin etc.
For forward grouping, typing and direct antiglobulin tests, a suspension of patient red cells is added to the top of the microtubes and for reverse ABO grouping, antibody screen or identification a mixture of patient red cells or reagent red cells with patient serum or reagent is added to appropriate microtubes.
The addition is then followed by centrifugation in a specially devised card centrifuge under controlled centrifugal force and time. In negative reactions the antibodies do not attach the red cells and the red cells freely pass through the gel and pellet to the bottom of the microtube. Conversely in a positive reaction the agglutinates are trapped in the gel to various degrees based on the degree of agglutination.
Matrix gel system, utilisies the gel column agglutination technology offers many end user benefit to the laboratarian imparting sensitivity and objectivity to immunohamatological analysis.
Advantages of Matrix Gel system:
Objective Interpretation of results
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